Case Study Quiz - Pernicious Anemia

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Case Study: Ella, a 58-year-old office assistant, presents to a clinic complaining of chronic stomach irritation, fatigue, weight loss, and tingling in her fingers. She reports that she takes a multivitamin every day.  A series of lab tests are run as well as endoscopic examination of the stomach and on the basis of the results she is diagnosed with chronic fundal (atrophic) gastritis and pernicious anemia.

Laboratory findings:

Mean corpuscular volume                High
Mean corpuscular hemoglobin         Normal
     concentration                          
Hematocrit                                     Low
Serum iron                                     Normal
Total iron-binding capacity               Normal
Serum folate                                  Normal
Serum cobalamin                           Low
Schilling test, stage 1                     Abnormal
Schilling test, stage 2                     Normal